{"dataType": "CVE_RECORD", "dataVersion": "5.2", "cveMetadata": {"cveId": "CVE-2026-17583", "assignerOrgId": "7d14cffa-0d7d-4270-9dc0-52cabd5a23a6", "state": "PUBLISHED", "assignerShortName": "icscert", "dateReserved": "2026-07-27T15:53:40.951Z", "datePublished": "2026-08-05T20:23:32.890Z", "dateUpdated": "2026-08-06T13:34:57.240Z"}, "containers": {"cna": {"providerMetadata": {"orgId": "7d14cffa-0d7d-4270-9dc0-52cabd5a23a6", "shortName": "icscert", "dateUpdated": "2026-08-05T20:23:32.890Z"}, "title": "Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check", "problemTypes": [{"descriptions": [{"lang": "en", "cweId": "CWE-353", "description": "CWE-353", "type": "CWE"}]}], "affected": [{"vendor": "Thermo Fisher", "product": "Applied Biosystems 3500/3500xL Series Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "4.0.2", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "Applied Biosystems 3730/3730xL Series Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "5.0.2", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "1.2.5", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "Applied Biosystems SeqStudio Flex Series Instrument Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "1.2.0", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "Applied Biosystems GeneMapper ID-X Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "1.7.3", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "Applied Biosystems 3130 Series Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "4.1", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "ABI PRISM 3100/3100-Avant Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "2.0", "versionType": "custom"}], "defaultStatus": "unaffected"}, {"vendor": "Thermo Fisher", "product": "ABI PRISM 310 Data Collection Software", "versions": [{"status": "affected", "version": "0", "lessThanOrEqual": "3.1", "versionType": "custom"}], "defaultStatus": "unaffected"}], "descriptions": [{"lang": "en", "value": "The affected\n\nThermo Fisher Applied Biosystems Genetic Analyzers are\u00a0vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.", "supportingMedia": [{"type": "text/html", "base64": false, "value": "<span>The affected</span>\n\nThermo Fisher Applied Biosystems Genetic Analyzers are<span>&nbsp;vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.</span>"}]}], "references": [{"url": "https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf"}, {"url": "https://www.cisa.gov/news-events/ics-medical-advisories/icsma-26-216-01"}, {"url": "https://www.cve.org/CVERecord?id=CVE-2026-17583"}], "metrics": [{"format": "CVSS", "scenarios": [{"lang": "en", "value": "GENERAL"}], "cvssV3_1": {"version": "3.1", "attackVector": "LOCAL", "attackComplexity": "LOW", "privilegesRequired": "NONE", "userInteraction": "NONE", "scope": "UNCHANGED", "confidentialityImpact": "HIGH", "integrityImpact": "HIGH", "availabilityImpact": "HIGH", "baseSeverity": "HIGH", "baseScore": 8.4, "vectorString": "CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H"}}, {"format": "CVSS", "scenarios": [{"lang": "en", "value": "GENERAL"}], "cvssV4_0": {"attackVector": "LOCAL", "attackComplexity": "LOW", "attackRequirements": "NONE", "privilegesRequired": "NONE", "userInteraction": "NONE", "vulnConfidentialityImpact": "NONE", "subConfidentialityImpact": "NONE", "vulnIntegrityImpact": "HIGH", "subIntegrityImpact": "HIGH", "vulnAvailabilityImpact": "HIGH", "subAvailabilityImpact": "NONE", "exploitMaturity": "NOT_DEFINED", "Safety": "NOT_DEFINED", "Automatable": "NOT_DEFINED", "Recovery": "NOT_DEFINED", "valueDensity": "NOT_DEFINED", "vulnerabilityResponseEffort": "NOT_DEFINED", "providerUrgency": "NOT_DEFINED", "version": "4.0", "baseSeverity": "HIGH", "baseScore": 8.3, "vectorString": "CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:H/SC:N/SI:H/SA:N"}}], "workarounds": [{"lang": "en", "value": "Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided\nABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided\nABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided\n\n\n\nFor users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed:\u00a0\n\n * Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow.\n * Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).\n * Restrict access to generated files to authorized personnel in accordance with your laboratory's access control policies.\n * Apply the principle of least privilege by limiting user permissions on systems operating the HID instrumentation or hosting associated data analysis and secondary analysis software.\n * Leverage firewall rules and network access control lists (NACLs) to restrict internet connectivity to only trusted sources.\n\n\n\n\nFor more information, refer to Thermo Fisher's security bulletin.\n https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf", "supportingMedia": [{"type": "text/html", "base64": false, "value": "<p>Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided<br>ABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided<br>ABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided</p><p>For users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed:&nbsp;</p><ul><li>Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow.</li><li>Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).</li><li>Restrict access to generated files to authorized personnel in accordance with your laboratory's access control policies.</li><li>Apply the principle of least privilege by limiting user permissions on systems operating the HID instrumentation or hosting associated data analysis and secondary analysis software.</li><li>Leverage firewall rules and network access control lists (NACLs) to restrict internet connectivity to only trusted sources.</li></ul><p>For more information, refer to Thermo Fisher's security bulletin.<br><a href=\"https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf\">https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf</a></p>"}]}], "solutions": [{"lang": "en", "value": "Thermo Fisher has developed security updates to address the vulnerability. The security updates implement the use of digital signatures on the instrument software that adds an extralayer of protection. Moving forward, this will help users verify that data files have not been modified.\n\n\n\nApplied Biosystems 3500/3500xL Series Data Collection Software: Update to version 4.0.3\n https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe \n\n\n\nApplied Biosystems 3730/3730xL Series Data Collection Software: Update to version 5.0.3\n https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe \n\n\n\nApplied Biosystems SeqStudio Genetic Analyzer Data Collection Software: Update to version 1.2.6\n https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg \n\n\n\nApplied Biosystems SeqStudio Flex Series Instrument Software: Update to version 1.2.1\n https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg \n\n\n\nApplied Biosystems GeneMapper ID-X Software: Update to version 1.7.4\n https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe", "supportingMedia": [{"type": "text/html", "base64": false, "value": "<p>Thermo Fisher has developed security updates to address the vulnerability. The security updates implement the use of digital signatures on the instrument software that adds an extralayer of protection. Moving forward, this will help users verify that data files have not been modified.</p><p>Applied Biosystems 3500/3500xL Series Data Collection Software: Update to version 4.0.3<br><a href=\"https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe\">https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe</a></p><p>Applied Biosystems 3730/3730xL Series Data Collection Software: Update to version 5.0.3<br><a href=\"https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe\">https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe</a></p><p>Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: Update to version 1.2.6<br><a href=\"https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg\">https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg</a></p><p>Applied Biosystems SeqStudio Flex Series Instrument Software: Update to version 1.2.1<br><a href=\"https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg\">https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg</a></p><p>Applied Biosystems GeneMapper ID-X Software: Update to version 1.7.4<br><a href=\"https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe\">https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe</a></p>"}]}], "credits": [{"lang": "en", "value": "Nathaniel Adams, Laura Gaydosh-Combs, and Kevin Dyer reported this vulnerability to CISA.", "type": "finder"}], "source": {"advisory": "ICSMA-26-216-01", "discovery": "EXTERNAL"}, "x_generator": {"engine": "Vulnogram 1.0.4"}}, "adp": [{"metrics": [{"other": {"type": "ssvc", "content": {"timestamp": "2026-08-06T13:34:47.788856Z", "id": "CVE-2026-17583", "options": [{"Exploitation": "none"}, {"Automatable": "no"}, {"Technical Impact": "total"}], "role": "CISA Coordinator", "version": "2.0.3"}}}], "title": "CISA ADP Vulnrichment", "providerMetadata": {"orgId": "134c704f-9b21-4f2e-91b3-4a467353bcc0", "shortName": "CISA-ADP", "dateUpdated": "2026-08-06T13:34:57.240Z"}}]}}

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The security updates implement the use of digital signatures on the instrument software that adds an extralayer of protection. Moving forward, this will help users verify that data files have not been modified.\n\n\n\nApplied Biosystems 3500/3500xL Series Data Collection Software: Update to version 4.0.3\n https://downloads.thermofisher.com/3500_DCS_v4.0.3_Patch/v4.0.3_Patch_Installer.exe \n\n\n\nApplied Biosystems 3730/3730xL Series Data Collection Software: Update to version 5.0.3\n https://downloads.thermofisher.com/3730xl_UDC_v5.0.3_Patch/3730xl_UDC_v5.0.3_Patch.exe \n\n\n\nApplied Biosystems SeqStudio Genetic Analyzer Data Collection Software: Update to version 1.2.6\n https://downloads.thermofisher.com/SeqStudio/1.2.6/SeqStudio-1.2.6.abpkg \n\n\n\nApplied Biosystems SeqStudio Flex Series Instrument Software: Update to version 1.2.1\n https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg \n\n\n\nApplied Biosystems GeneMapper ID-X Software: Update to version 1.7.4\n https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe", "supportingMedia": [{"type": "text/html", "value": "<p>Thermo Fisher has developed security updates to address the vulnerability. 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version 1.2.1<br><a href=\"https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg\">https://downloads.thermofisher.com/SeqStudioFlex/1.2.1/SeqStudioFlex-1.2.1.abpkg</a></p><p>Applied Biosystems GeneMapper ID-X Software: Update to version 1.7.4<br><a href=\"https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe\">https://downloads.thermofisher.com/GeneMapperID-Xv1.7.4_Patch/GMIDX_v1.7.4_Patch.exe</a></p>", "base64": false}]}], "references": [{"url": "https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf"}, {"url": "https://www.cisa.gov/news-events/ics-medical-advisories/icsma-26-216-01"}, {"url": "https://www.cve.org/CVERecord?id=CVE-2026-17583"}], "workarounds": [{"lang": "en", "value": "Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided\nABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided\nABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided\n\n\n\nFor users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed:\u00a0\n\n * Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow.\n * Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).\n * Restrict access to generated files to authorized personnel in accordance with your laboratory's access control policies.\n * Apply the principle of least privilege by limiting user permissions on systems operating the HID instrumentation or hosting associated data analysis and secondary analysis software.\n * Leverage firewall rules and network access control lists (NACLs) to restrict internet connectivity to only trusted sources.\n\n\n\n\nFor more information, refer to Thermo Fisher's security bulletin.\n https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf", "supportingMedia": [{"type": "text/html", "value": "<p>Applied Biosystems 3130 Series Data Collection Software: Product is End of Life (EoL), no update provided<br>ABI PRISM 3100/3100-Avant Data Collection Software: Product is End of Life (EoL), no update provided<br>ABI PRISM 310 Data Collection Software: Product is End of Life (EoL), no update provided</p><p>For users who are unable to immediately implement all applicable security updates, Thermo Fisher Scientific recommends implementing the following interim mitigation measures until the applicable updates have been installed:&nbsp;</p><ul><li>Maintain a secure chain of custody for files generated by the HID instrumentation throughout the analysis workflow.</li><li>Store generated files on encrypted, password-protected storage media (for example, encrypted USB drives or encrypted hard drives).</li><li>Restrict access to generated files to authorized personnel in accordance with your laboratory's access control policies.</li><li>Apply the principle of least privilege by limiting user permissions on systems operating the HID instrumentation or hosting associated data analysis and secondary analysis software.</li><li>Leverage firewall rules and network access control lists (NACLs) to restrict internet connectivity to only trusted sources.</li></ul><p>For more information, refer to Thermo Fisher's security bulletin.<br><a href=\"https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf\">https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf</a></p>", "base64": false}]}], "x_generator": {"engine": "Vulnogram 1.0.4"}, "descriptions": [{"lang": "en", "value": "The affected\n\nThermo Fisher Applied Biosystems Genetic Analyzers are\u00a0vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.", "supportingMedia": [{"type": "text/html", "value": "<span>The affected</span>\n\nThermo Fisher Applied Biosystems Genetic Analyzers are<span>&nbsp;vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.</span>", "base64": false}]}], "problemTypes": [{"descriptions": [{"lang": "en", "type": "CWE", "cweId": "CWE-353", "description": "CWE-353"}]}], "providerMetadata": {"orgId": "7d14cffa-0d7d-4270-9dc0-52cabd5a23a6", "shortName": "icscert", "dateUpdated": "2026-08-05T20:23:32.890Z"}}, "adp": [{"title": "CISA ADP Vulnrichment", "metrics": [{"other": {"type": "ssvc", "content": {"id": "CVE-2026-17583", "role": "CISA Coordinator", "options": [{"Exploitation": "none"}, {"Automatable": "no"}, {"Technical Impact": "total"}], "version": "2.0.3", "timestamp": "2026-08-06T13:34:47.788856Z"}}}], "providerMetadata": {"shortName": "CISA-ADP", "orgId": "134c704f-9b21-4f2e-91b3-4a467353bcc0", "dateUpdated": "2026-08-06T13:34:53.973Z"}}]}, "cveMetadata": {"cveId": "CVE-2026-17583", "state": "PUBLISHED", "dateUpdated": "2026-08-05T20:23:32.890Z", "dateReserved": "2026-07-27T15:53:40.951Z", "assignerOrgId": "7d14cffa-0d7d-4270-9dc0-52cabd5a23a6", "datePublished": "2026-08-05T20:23:32.890Z", "assignerShortName": "icscert"}, "dataVersion": "5.2"}

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{"created": "2026-08-05T21:30:16.323826+00:00", "updated": "2026-08-05T21:30:16.323834+00:00", "vendors": []}